In collaboration with the Global Forum on Bioethics in Research (GFBR), the Southeast Asia Bioethics Network organised an insightful two-day workshop on the ethics oversight of AI-driven health (AIH) research. Held on 22nd - 23rd January 2024, at Faculty of Law, Universiti Malaya, Malaysia, the workshop brought together experts and stakeholders to delve into the complex ethical dimensions inherent in AI-driven health research, particularly in Low and Middle-Income Countries (LMICs). The workshop aimed to explore the pressing need for a distinct approach to ethical oversight of AIH research, given the transformative impact of artificial intelligence on health research practices. Through a series of individual presentations and group discussions, participants engaged in critical discourse surrounding the ethical considerations specific to AIH research, considering its implications within the Malaysian context and beyond. Central to the workshop's agenda was the exploration of whether innovative approaches to ethics oversight should be established in the domain of AIH research. Participants deliberated on the feasibility and challenges of implementing such approaches in LMIC contexts, considering the diverse socio-cultural and regulatory landscapes that characterise these regions. Subsequent discussions delved deeper into the unique ethical considerations posed by AIH research, comparing global approaches to ethics oversight, and scrutinising governance in international collaborative projects. Participants also examined various forms of AIH research in LMICs and the corresponding ethical oversight mechanisms, aiming to identify best practices and areas for improvement. In collaboration with the GFBR, the workshop served as a crucible of insights, fostering nuanced discussions on the evolving ethical standards in AI-Driven Health Research within the Malaysian context. The event provided a platform for stakeholders to exchange perspectives, share experiences and collectively chart a course towards enhancing ethics oversight in AIH research, ultimately ensuring the responsible and equitable advancement of healthcare technologies. Moving forward, the insights and recommendations generated from the workshop will inform ongoing efforts to strengthen ethics oversight frameworks, promote transparency and uphold ethical principles in AI-driven health research initiatives across Malaysia and beyond.